KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHP3
All Species:
17.58
Human Site:
S588
Identified Species:
42.96
UniProt:
Q7Z494
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z494
NP_694972.3
1330
150864
S588
K
L
M
Q
H
S
W
S
V
S
A
L
T
L
D
Chimpanzee
Pan troglodytes
XP_516758
2073
234018
S601
K
L
M
Q
H
S
W
S
V
S
A
L
T
L
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863943
2040
230770
S568
K
L
M
Q
H
S
W
S
V
S
A
L
T
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNH6
1324
150168
A584
K
L
M
Q
H
F
W
A
V
S
A
L
T
L
D
Rat
Rattus norvegicus
XP_343462
1325
150597
A584
K
L
M
Q
H
F
W
A
V
S
A
L
T
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514031
1275
145541
F546
P
G
K
L
L
E
E
F
P
R
W
L
E
K
L
Chicken
Gallus gallus
XP_418790
1315
149161
L572
K
L
M
Q
H
S
W
L
V
S
P
L
T
L
D
Frog
Xenopus laevis
Q6AZT7
1300
148301
S560
K
L
M
Q
H
S
W
S
V
S
S
L
S
M
D
Zebra Danio
Brachydanio rerio
XP_691073
1303
148244
S566
K
L
L
Q
H
F
W
S
I
S
G
L
S
M
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203493
1012
113472
C312
R
Q
R
E
V
E
Y
C
T
I
F
V
G
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
N.A.
61.5
N.A.
88.8
87.9
N.A.
78
83.9
76.9
69.9
N.A.
N.A.
N.A.
N.A.
30.9
Protein Similarity:
100
62.4
N.A.
63
N.A.
93.3
93.3
N.A.
86.2
90.7
86.5
82.9
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
6.6
86.6
80
60
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
6.6
86.6
100
86.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
20
0
0
50
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% D
% Glu:
0
0
0
10
0
20
10
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
30
0
10
0
0
10
0
0
10
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
10
0
10
0
0
% G
% His:
0
0
0
0
80
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% I
% Lys:
80
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
80
10
10
10
0
0
10
0
0
0
90
0
60
20
% L
% Met:
0
0
70
0
0
0
0
0
0
0
0
0
0
20
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% P
% Gln:
0
10
0
80
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
50
0
50
0
80
10
0
20
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
60
0
0
% T
% Val:
0
0
0
0
10
0
0
0
70
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
80
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _